Phytochemical and pharmacological reports of the hypoglycemic activity of the Moringa oleifera extracts

Abstract Moringa oleifera is an arboreal plant belonging to the family Moringaceae distributed in tropical areas and has gained enormous attention last decades. This research a review on association between aqueous extracts of M. leaves diabetes mellitus understanding its pharmacological functions underlying mechanisms. The refinement demonstrated pharmaceutical potential phytochemicals, given antidiabetic effect. prospective analysis showed amount application within IPC A61K health area. secondary metabolites present oleifera, glucosinolates, flavonoids, phenolic compounds may be responsible, part, for disease control hypoglycemic actions. Glucosinolates, when metabolized by salivary enzymes, give rise sulforaphanes that act preventing type 2 reducing insulin resistance. Flavonoids interact with intestinal enzymes modifying carbohydrate metabolism regulating glycemic levels, addition increasing sensitivity. Phenolic increase expression glucose transporters (GLUT4) reduce synthesis fatty acids cholesterol, contributing reduction resistance blood sugar control. can used as complementary therapy type-2 diabetes.